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what is pathophysiology

Definition

Pathophysiology (consisting of the Greek origin words “pathos” = suffering; “physis” = nature, origin; and “logos” = “the study of”) refers to the study of abnormal changes in body functions that are the causes, consequences, or concomitants of disease processes. Studies of pathophysiology are concerned with the investigation of biological processes that are directly related to disease processes of physical, mental, or psychophysiological conditions and disorders (e.g., alterations in the endocrine system, in certain neurotransmitters, or inflammatory parameters related to the activity of the immune system). Thus, pathophysiological research aims at identifying biological markers and mechanisms for predicting and explaining disease processes in terms of etiology and pathogenesis. Pathophysiology is formally considered as a subdiscipline within physiology.

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